RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
miR-17-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
LINCRNA-P21
Pathway
WNT SIGNALING PATHWAY; CATENIN BETA 1
PubMed ID
Title
LincRNA-p21 Inhibits the Wnt/B-Catenin Pathway in Activated Hepatic Stellate Cells via Sponging MicroRNA-17-5p
Year
2017
Function
"Lincrna-p21 inhibits hepatic stellate cell activation by inhibiting the wnt ; B-catenin pathway, whereas microrna-17-5p can block this effect of lincrna-p21, reactivating lincrna-p21-inhibited wnt ; Beta-catenin pathway."